Preprints
We believe in disseminating research products of all kinds. We pre-print all work before publication and we highlight pre-printed work that is under review, when appropriate.
An engineered, orthogonal auxin analog/AtTIR1(F79G) pairing improves both specificity and efficacy of the auxin degradation system in Caenorhabditis elegans
Kelly Hills-Muckey, Michael A. Q. Martinez, Natalia Stec, Shilpa Hebbar, Joanne Saldanha, Taylor N. Medwig-Kinney, Frances E. Q. Moore, Mariia Ivanova, Ana Morao, Jordan D. Ward, Eric G. Moss, Sevinc Ercan, Anna Y. Zinovyeva, David Q. Matus, Christopher M. Hammell
bioRxiv 2021.08.06.455414; doi: https://doi.org/10.1101/2021.08.06.455414
The conserved molting/circadian rhythm regulator NHR-23/NR1F1 serves as an essential co-regulator of C. elegans spermatogenesis
James Matthew Ragle, Abigail L. Aita, Kayleigh N. Morrison, Raquel Martinez-Mendez, Hannah N. Saeger, Guinevere A. Ashley, Londen C. Johnson, Katherine A. Schubert, Diane C. Shakes, Jordan D. Ward
bioRxiv 2020.06.11.147298; doi: https://doi.org/10.1101/2020.06.11.147298
Expanding the Caenorhabditis elegans auxin-inducible degron system toolkit with internal expression and degradation controls and improved modular constructs for CRISPR/Cas9-mediated genome editing
Guinevere Ashley, Tam Duong, Max T. Levenson, Michael A. Q. Martinez, Jonathan D. Hibshman, Hannah N. Saeger, Ryan Doonan, Nicholas J. Palmisano, Raquel Martinez-Mendez, Brittany Davidson, Wan Zhang, James Matthew Ragle, Taylor N. Medwig-Kinney, Sydney S. Sirota, Bob Goldstein, David Q. Matus, Daniel J. Dickinson, David J. Reiner, Jordan D. Ward
bioRxiv 2020.05.12.090217; doi: https://doi.org/10.1101/2020.05.12.090217
Rapid degradation of C. elegans proteins at single-cell resolution with a synthetic auxin
Michael A. Q. Martinez, Brian A. Kinney, Taylor N. Medwig-Kinney, Guinevere Ashley, James M. Ragle, Londen Johnson, Joseph Aguilera, Christopher M. Hammell, Jordan D. Ward, David Q. Matus
bioRxiv 716837; doi: https://doi.org/10.1101/716837
The glucocorticoid receptor ligand-binding domain confers drug-gated protein regulation in C. elegans
Gabriela C. Monsalve, Keith R. Yamamoto, Jordan D. Ward
bioRxiv 445833; doi: https://doi.org/10.1101/445833
Kelly Hills-Muckey, Michael A. Q. Martinez, Natalia Stec, Shilpa Hebbar, Joanne Saldanha, Taylor N. Medwig-Kinney, Frances E. Q. Moore, Mariia Ivanova, Ana Morao, Jordan D. Ward, Eric G. Moss, Sevinc Ercan, Anna Y. Zinovyeva, David Q. Matus, Christopher M. Hammell
bioRxiv 2021.08.06.455414; doi: https://doi.org/10.1101/2021.08.06.455414
The conserved molting/circadian rhythm regulator NHR-23/NR1F1 serves as an essential co-regulator of C. elegans spermatogenesis
James Matthew Ragle, Abigail L. Aita, Kayleigh N. Morrison, Raquel Martinez-Mendez, Hannah N. Saeger, Guinevere A. Ashley, Londen C. Johnson, Katherine A. Schubert, Diane C. Shakes, Jordan D. Ward
bioRxiv 2020.06.11.147298; doi: https://doi.org/10.1101/2020.06.11.147298
Expanding the Caenorhabditis elegans auxin-inducible degron system toolkit with internal expression and degradation controls and improved modular constructs for CRISPR/Cas9-mediated genome editing
Guinevere Ashley, Tam Duong, Max T. Levenson, Michael A. Q. Martinez, Jonathan D. Hibshman, Hannah N. Saeger, Ryan Doonan, Nicholas J. Palmisano, Raquel Martinez-Mendez, Brittany Davidson, Wan Zhang, James Matthew Ragle, Taylor N. Medwig-Kinney, Sydney S. Sirota, Bob Goldstein, David Q. Matus, Daniel J. Dickinson, David J. Reiner, Jordan D. Ward
bioRxiv 2020.05.12.090217; doi: https://doi.org/10.1101/2020.05.12.090217
Rapid degradation of C. elegans proteins at single-cell resolution with a synthetic auxin
Michael A. Q. Martinez, Brian A. Kinney, Taylor N. Medwig-Kinney, Guinevere Ashley, James M. Ragle, Londen Johnson, Joseph Aguilera, Christopher M. Hammell, Jordan D. Ward, David Q. Matus
bioRxiv 716837; doi: https://doi.org/10.1101/716837
The glucocorticoid receptor ligand-binding domain confers drug-gated protein regulation in C. elegans
Gabriela C. Monsalve, Keith R. Yamamoto, Jordan D. Ward
bioRxiv 445833; doi: https://doi.org/10.1101/445833